Macrophage type 2 differentiation in a patient with laryngeal squamous cell carcinoma and metastatic prostate adenocarcinoma to the cervical lymph nodes

Macrophage type 2 differentiation in a patient with laryngeal squamous cell carcinoma and metastatic prostate adenocarcinoma to the cervical lymph nodes

Abstract Background The tumor microenvironment often polarizes infiltrating macrophages towards a type 2, or M2 phenotype, that is characterized by expression of various cysteine-rich, scavenger receptors, including CD163. The primary function of M2 macrophages is to facilitate wound healing. As suc...

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Bibliographic Details
Main Authors: Michael C. Topf, Madalina Tuluc, Larry A. Harshyne, Adam Luginbuhl
Format: Article
Language:English
Published: BMJ Publishing Group 2017-07-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
M2 macrophages
CD163
Tumor microenvironment
Online Access:http://link.springer.com/article/10.1186/s40425-017-0264-z

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http://link.springer.com/article/10.1186/s40425-017-0264-z

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