Bmi1 Suppresses Adipogenesis in the Hematopoietic Stem Cell Niche

Summary: Bone marrow stromal cells (BMSCs) that express high levels of stem cell factor (SCF) and CXC chemokine ligand 12 (CXCL12) are one crucial component of the hematopoietic stem cell (HSC) niche. While the secreted factors produced by BMSCs to support HSCs have been well described, little is kn...

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Bibliographic Details
Main Authors: Tianyuan Hu, Ayumi Kitano, Victor Luu, Brian Dawson, Kevin A. Hoegenauer, Brendan H. Lee, Daisuke Nakada
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221367111930195X