Neutrophils Inhibit Synthesis of Mineralized Extracellular Matrix by Human Bone Marrow-Derived Stromal Cells In Vitro

Neutrophils Inhibit Synthesis of Mineralized Extracellular Matrix by Human Bone Marrow-Derived Stromal Cells In Vitro

Although controlled local inflammation is essential for adequate bone regeneration, several studies have shown that hyper-inflammatory conditions after major trauma are associated with impaired fracture healing. These hyper-inflammatory conditions include the trauma-induced systemic inflammatory res...

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Bibliographic Details
Main Authors: Okan W. Bastian, Michiel Croes, Jacqueline Alblas, Leo Koenderman, Luke P. H. Leenen, Taco J. Blokhuis
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
neutrophils
bone regeneration
fracture healing
stromal cells
bone marrow stromal cell
multipotent stromal cell
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00945/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00945/full

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