Enhanced expressions of neurodegeneration-associated factors, UPS impairment, and excess Aβ accumulation in the hippocampus of mice with persistent cerebral toxocariasis

Enhanced expressions of neurodegeneration-associated factors, UPS impairment, and excess Aβ accumulation in the hippocampus of mice with persistent cerebral toxocariasis

Abstract Background Toxocariasis is a worldwide zoonotic parasitic disease mainly caused by Toxocara canis. Humans can be infected by accidental ingestion of T. canis embryonated ovum-contaminated food, water, or encapsulated larvae in paratenic hosts’ viscera or meat. Since humans and mice are para...

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Bibliographic Details
Main Authors: Chia-Mei Chou, Yueh-Lun Lee, Chien-Wei Liao, Ying-Chieh Huang, Chia-Kwung Fan
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Parasites & Vectors
Subjects:
Cerebral toxocariasis
Toxocara canis
Zoonosis
Mice
Hippocampus
Amyloid β
Online Access:http://link.springer.com/article/10.1186/s13071-017-2578-6

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http://link.springer.com/article/10.1186/s13071-017-2578-6

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