Enhancement of inhibitory neurotransmission and inhibition of excitatory mechanisms underlie the anticonvulsant effects of Mallotus oppositifolius

Enhancement of inhibitory neurotransmission and inhibition of excitatory mechanisms underlie the anticonvulsant effects of Mallotus oppositifolius

Context: Mallotus oppositifolius is a shrub that is used traditionally to treat epilepsy, but its potential has not been scientifically validated. Aims: This study investigated the anticonvulsant properties and possible mechanism of action of the 70% v/v hydroalcoholic extract of the leaves of M. op...

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Bibliographic Details
Main Authors: Kennedy Kwami Edem Kukuia, Elvis Ofori Ameyaw, Eric Woode, Priscilla Kolibea Mante, Donatus Wewura Adongo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Benzodiazepine/gamma-aminobutyric acid type A receptor
flumazenil
Mallotus oppositifolius
pilocarpine
seizures
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2016;volume=8;issue=3;spage=253;epage=261;aulast=Kukuia

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http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2016;volume=8;issue=3;spage=253;epage=261;aulast=Kukuia

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