Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells.

The orphan nuclear receptor COUP-TFII plays an undefined role in breast cancer. Previously we reported lower COUP-TFII expression in tamoxifen/endocrine-resistant versus sensitive breast cancer cell lines. The identification of COUP-TFII-interacting proteins will help to elucidate its mechanism of a...

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Main Authors: Lacey M Litchfield, Krista A Riggs, Alyson M Hockenberry, Laura D Oliver, Katelyn G Barnhart, Jian Cai, William M Pierce, Margarita M Ivanova, Paula J Bates, Savitri N Appana, Susmita Datta, Piotr Kulesza, Jean McBryan, Leonie S Young, Carolyn M Klinge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3365040?pdf=render