Characteristics of T-Cell Receptor Repertoire and Correlation With EGFR Mutations in All Stages of Lung Cancer

Characteristics of T-Cell Receptor Repertoire and Correlation With EGFR Mutations in All Stages of Lung Cancer

Lung cancer is the leading cause of cancer-related deaths worldwide, and its occurrence is related to the accumulation of gene mutations and immune escape of the tumor. Sequencing of the T-cell receptor (TCR) repertoire can reveal the immunosurveillance status of the tumor microenvironment, which is...

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Bibliographic Details
Main Authors: Huaxia Yang, Yadong Wang, Ziqi Jia, Yanyu Wang, Xiaoying Yang, Pancheng Wu, Yang Song, Huihui Xu, Dejian Gu, Rongrong Chen, Xuefeng Xia, Zhongxing Bing, Chao Gao, Lei Cao, Shanqing Li, Zhili Cao, Naixin Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
T-cell receptor repertoire
lung cancer
clonality
high-throughput sequencing
epidermal growth factor receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.537735/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.537735/full

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