Magnesium lithospermate B protects cardiomyocytes from ischemic injury via inhibition of TAB1-p38 apoptosis signaling

Magnesium lithospermate B protects cardiomyocytes from ischemic injury via inhibition of TAB1-p38 apoptosis signaling

Danshen has been used in traditional Chinese medicine (TCM) for hundreds of years to treat cardiovascular diseases. However, its precise cardioprotective components and the underlying mechanism are still unclear. In the present study, we demonstrated that in a rat model of acute myocardial infarctio...

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Bibliographic Details
Main Authors: Chang-Sheng Du, Rui-Fang Yang, Shu-Wei Song, Yi-Ping Wang, Jiu-Hong Kang, Ru Zhang, Ding-Feng Su, Xin Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-08-01
Series:Frontiers in Pharmacology
Subjects:
Apoptosis
Ischemia
Magnesium lithospermate B
p38
TAB1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2010.00111/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2010.00111/full

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