The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation

When using human induced pluripotent stem cells (hiPSCs) to achieve hair follicle (HF) replacement, we found it best to emulate the earliest fundamental developmental processes of gastrulation, ectodermal lineage commitment, and dermogenesis. Viewing hiPSCs as a model of the epiblast, we exploited i...

Full description

Bibliographic Details
Main Authors: Michel R. Ibrahim, Walid Medhat, Hasan El-Fakahany, Hamza Abdel-Raouf, Evan Y. Snyder
Format: Article
Language:English
Published: SAGE Publishing 2021-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897211014820