Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia

Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia

Abstract Background Azithromycin (Azm) is a macrolide recognized for its disease-modifying effects and reduction in exacerbation of chronic airway diseases. It is not clear whether the beneficial effects of Azm are due to its anti-microbial activity or other pharmacological actions. We have shown th...

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Bibliographic Details
Main Authors: Ari Jon Arason, Jon Petur Joelsson, Bryndis Valdimarsdottir, Snaevar Sigurdsson, Alexander Gudjonsson, Skarphedinn Halldorsson, Freyr Johannsson, Ottar Rolfsson, Fredrik Lehmann, Saevar Ingthorsson, Paulina Cherek, Gudmundur H. Gudmundsson, Fridrik R. Gardarsson, Clive P. Page, Olafur Baldursson, Thorarinn Gudjonsson, Jennifer A. Kricker
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Respiratory Research
Subjects:
Azithromycin
Air-liquid interface
Gene expression
Airway
Epithelia
Epidermal differentiation
Online Access:http://link.springer.com/article/10.1186/s12931-019-1101-3

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http://link.springer.com/article/10.1186/s12931-019-1101-3

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