Increased mucosal neutrophil survival is associated with altered microbiota in HIV infection.

Gastrointestinal (GI) mucosal dysfunction predicts and likely contributes to non-infectious comorbidities and mortality in HIV infection and persists despite antiretroviral therapy. However, the mechanisms underlying this dysfunction remain incompletely understood. Neutrophils are important for cont...

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Bibliographic Details
Main Authors: Tiffany Hensley-McBain, Michael C Wu, Jennifer A Manuzak, Ryan K Cheu, Andrew Gustin, Connor B Driscoll, Alexander S Zevin, Charlene J Miller, Ernesto Coronado, Elise Smith, Jean Chang, Michael Gale, Ma Somsouk, Adam D Burgener, Peter W Hunt, Thomas J Hope, Ann C Collier, Nichole R Klatt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007672