ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease

ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease

Recent epidemiological, biological and genetic data indicate a relationship between cholesterol and Alzheimer's disease (AD) including the association of polymorphisms of ABCA1 (a gene that is known to participate in cholesterol and phospholipid transport) with AD prevalence. Based on these dat...

Full description

Bibliographic Details
Main Authors: Sandrine Macé, Emmanuelle Cousin, Sylvain Ricard, Emmanuelle Génin, Emmanuel Spanakis, Carole Lafargue-Soubigou, Bérengère Génin, Raphaël Fournel, Sandrine Roche, Gilles Haussy, Florence Massey, Stéphane Soubigou, Georges Bréfort, Patrick Benoit, Alexis Brice, Dominique Campion, Melvyn Hollis, Laurent Pradier, Jésus Benavides, Jean-François Deleuze
Format: Article
Language:English
Published: Elsevier 2005-02-01
Series:Neurobiology of Disease
Subjects:
Association study
Alzheimer's disease
ABCA2
Cholesterol
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104002207

Internet

http://www.sciencedirect.com/science/article/pii/S0969996104002207

Similar Items