Nonconserved miR‐608 suppresses prostate cancer progression through RAC2/PAK4/LIMK1 and BCL2L1/caspase‐3 pathways by targeting the 3′‐UTRs of RAC2/BCL2L1 and the coding region of PAK4
Abstract The aim of this study is to investigate the functions and mechanisms of miR‐608 in prostate cancer (PCa). CISH and qRT‐PCR analysis demonstrated that miR‐608 was low expressed in PCa tissues and cells, which was partly attributed to the methylation of CpG island adjacent to the transcriptio...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-09-01
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| Series: | Cancer Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cam4.2455 |