Small interfering RNA targeted to stem-loop II of the 5' untranslated region effectively inhibits expression of six HCV genotypes
<p>Abstract</p> <p>Background</p> <p>The antiviral action of interferon alpha targets the 5' untranslated region (UTR) used by hepatitis C virus (HCV) to translate protein by an internal ribosome entry site (IRES) mechanism. Although this sequence is highly conserv...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-11-01
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| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/3/1/100 |