Intrachromosomal colocalization strengthens co-expression, co-modification and evolutionary conservation of neighboring genes

Abstract Background Gene order and location in chromosomes of species are non-random. Neighboring gene pairs tend to display some similarities, such as co-expression and co-modification. However, the contribution of linear proximity, spatial proximity, and evolutionary proximity to these similaritie...

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Bibliographic Details
Main Authors: Shuaibin Lian, Tianliang Liu, Shengli Jing, Hongyu Yuan, Zaibao Zhang, Lin Cheng
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-018-4844-1