Functionality of in vitro reconstituted group II intron RmInt1-derived ribonucleoprotein particles

The functional unit of mobile group II introns is a ribonucleoprotein particle (RNP) consisting of the intron-encoded protein (IEP) and the excised intron RNA. The IEP has reverse transcriptase activity but also promotes RNA splicing, and the RNA-protein complex triggers site-specific DNA insertion...

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Bibliographic Details
Main Authors: María Dolores Molina-Sánchez, Fernando Manuel García-Rodríguez, Nicolas Toro
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2016.00058/full