Chemotherapy-induced monoamine oxidase expression in prostate carcinoma functions as a cytoprotective resistance enzyme and associates with clinical outcomes.

To identify molecular alterations in prostate cancers associating with relapse following neoadjuvant chemotherapy and radical prostatectomy patients with high-risk localized prostate cancer were enrolled into a phase I-II clinical trial of neoadjuvant chemotherapy with docetaxel and mitoxantrone fol...

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Bibliographic Details
Main Authors: Ryan R Gordon, Mengchu Wu, Chung-Ying Huang, William P Harris, Hong Gee Sim, Jared M Lucas, Ilsa Coleman, Celestia S Higano, Roman Gulati, Lawrence D True, Robert Vessella, Paul H Lange, Mark Garzotto, Tomasz M Beer, Peter S Nelson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4157741?pdf=render