Results and Clinical Interpretation of Germline <i>RET</i> Analysis in a Series of Patients with Medullary Thyroid Carcinoma: The Challenge of the Variants of Uncertain Significance

Results and Clinical Interpretation of Germline <i>RET</i> Analysis in a Series of Patients with Medullary Thyroid Carcinoma: The Challenge of the Variants of Uncertain Significance

Germline <i>RET</i> variants are responsible for approximately 25% of medullary thyroid carcinoma (MTC) cases. Identification of <i>RET</i> variant carriers allows for the adoption of preventative measures which are dependent on the risk associated with the specific alteratio...

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Bibliographic Details
Main Authors: Giovanni Innella, Cesare Rossi, Maria Romagnoli, Andrea Repaci, Davide Bianchi, Maria Elena Cantarini, Davide Martorana, Lea Godino, Andrea Pession, Antonio Percesepe, Uberto Pagotto, Daniela Turchetti
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
<i>RET</i>
medullary thyroid carcinoma
clinical management
variants of uncertain significance
Online Access:https://www.mdpi.com/2072-6694/12/11/3268

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https://www.mdpi.com/2072-6694/12/11/3268

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