Dengue Virus Directly Stimulates Polyclonal B Cell Activation.

Dengue infection is associated to vigorous inflammatory response, to a high frequency of activated B cells, and to increased levels of circulating cross-reactive antibodies. We investigated whether direct infection of B cells would promote activation by culturing primary human B lymphocytes from hea...

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Bibliographic Details
Main Authors: Arturo Ramon Vargas Correa, Ana Carolina Egypto Rosa Berbel, Michelle Premazzi Papa, Ana Theresa Silveira de Morais, Ligia Maria Torres Peçanha, Luciana Barros de Arruda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4675537?pdf=render