Spontaneous clearance of viral infections by mesoscopic fluctuations.

Spontaneous disease extinction can occur due to a rare stochastic fluctuation. We explore this process, both numerically and theoretically, in two minimal models of stochastic viral infection dynamics. We propose a method that reduces the complexity in models of viral infections so that the remainin...

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Bibliographic Details
Main Authors: Srabanti Chaudhury, Alan S Perelson, Nikolai A Sinitstyn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3367925?pdf=render