Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients

Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients

Summary: Virus-specific humoral and cellular immunity act synergistically to protect the host from viral infection. We interrogate the dynamic changes of virological and immunological parameters in 12 patients with symptomatic acute SARS-CoV-2 infection from disease onset to convalescence or death....

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Bibliographic Details
Main Authors: Anthony T. Tan, Martin Linster, Chee Wah Tan, Nina Le Bert, Wan Ni Chia, Kamini Kunasegaran, Yan Zhuang, Christine Y.L. Tham, Adeline Chia, Gavin J.D. Smith, Barnaby Young, Shirin Kalimuddin, Jenny G.H. Low, David Lye, Lin-Fa Wang, Antonio Bertoletti
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Cell Reports
Subjects:
T cell response
Longitudinal
Acute phase4
Convalescence
Humoral response
Antibodies
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721000413

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http://www.sciencedirect.com/science/article/pii/S2211124721000413

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