Comparative analysis of neuroinvasion by Japanese encephalitis virulent and vaccine viral strains in an in vitro model of human blood-brain barrier.

Japanese encephalitis virus (JEV) is the major cause of viral encephalitis in South East Asia. It has been suggested that, as a consequence of the inflammatory process during JEV infection, there is disruption of the blood-brain barrier (BBB) tight junctions that in turn allows the virus access to t...

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Bibliographic Details
Main Authors: Cécile Khou, Marco Aurelio Díaz-Salinas, Anaelle da Costa, Christophe Préhaud, Patricia Jeannin, Philippe V Afonso, Marco Vignuzzi, Monique Lafon, Nathalie Pardigon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0252595