Human Antimicrobial Peptide Hepcidin 25-Induced Apoptosis in <i>Candida albicans</i>

Hepcidin 25 (hep 25) is a cysteine-rich 25-amino acid antimicrobial peptide containing the amino-terminal Cu(II)/Ni(II)-binding (ATCUN) motif. Upon metal binding, the ATCUN motif is known to be involved in the generation of reactive oxygen species (ROS), especially hydrogen peroxide and hydroxyl rad...

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Bibliographic Details
Main Authors: Ruei-Ching Chen, Chung-Yu Lan
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/8/4/585