Oxidative stress evoked damages leading to attenuated memory and inhibition of NMDAR–CaMKII–ERK/CREB signalling on consumption of aspartame in rat model

Oxidative stress evoked damages leading to attenuated memory and inhibition of NMDAR–CaMKII–ERK/CREB signalling on consumption of aspartame in rat model

Many controversial reports are available on the use of aspartame as it releases methanol as one of its metabolite during metabolism. The present study proposes to investigate whether long term (90 days) aspartame (40 mg/kg b.wt) administration could induce oxidative stress and alter the memory in Wi...

Full description

Bibliographic Details
Main Authors: Ashok Iyaswamy, Ananth Kumar Kammella, Citarasu Thavasimuthu, Wankhar Wankupar, Wankhar Dapkupar, Sambantham Shanmugam, Ravindran Rajan, Sheeladevi Rathinasamy
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Journal of Food and Drug Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S1021949817302004

Internet

http://www.sciencedirect.com/science/article/pii/S1021949817302004

Similar Items