Oxidative stress evoked damages leading to attenuated memory and inhibition of NMDAR–CaMKII–ERK/CREB signalling on consumption of aspartame in rat model
Many controversial reports are available on the use of aspartame as it releases methanol as one of its metabolite during metabolism. The present study proposes to investigate whether long term (90 days) aspartame (40 mg/kg b.wt) administration could induce oxidative stress and alter the memory in Wi...
Main Authors: | Ashok Iyaswamy, Ananth Kumar Kammella, Citarasu Thavasimuthu, Wankhar Wankupar, Wankhar Dapkupar, Sambantham Shanmugam, Ravindran Rajan, Sheeladevi Rathinasamy |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-04-01
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Series: | Journal of Food and Drug Analysis |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1021949817302004 |
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