NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells

NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells

Summary: Spermatogonial stem cells (SSCs) sustain spermatogenesis and fertility throughout adult male life. The conserved RNA-binding protein NANOS2 is essential for the maintenance of SSCs, but its targets and mechanisms of function are not fully understood. Here, we generated a fully functional ep...

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Bibliographic Details
Main Authors: Azzurra Codino, Tomasz Turowski, Louie N. van de Lagemaat, Ivayla Ivanova, Andrea Tavosanis, Christian Much, Tania Auchynnikava, Lina Vasiliauskaitė, Marcos Morgan, Juri Rappsilber, Robin C. Allshire, Kamil R. Kranc, David Tollervey, Dónal O'Carroll
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Developmental biology
Omics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221007306

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http://www.sciencedirect.com/science/article/pii/S2589004221007306

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