Deletion of KIBRA, protein expressed in kidney and brain, increases filopodial-like long dendritic spines in neocortical and hippocampal neurons in vivo and in vitro
Spines are small protrusions arising from dendrites that receive most excitatory synaptic input in the brain. Dendritic spines represent dynamic structures that undergo activity-dependent adaptations, for example, during synaptic plasticity. Alterations of spine morphology, changes of spine type rat...
Main Authors: | Anja eBlanque, Daniele eRepetto, Astrid eRohlmann, Johannes eBrockhaus, Kerstin eDuning, Hermann ePavenstädt, Ilka eWolff, Markus eMissler |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-02-01
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Series: | Frontiers in Neuroanatomy |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnana.2015.00013/full |
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