Ameliorating end-product inhibition to improve cadaverine production in engineered Escherichia coli and its application in the synthesis of bio-based diisocyanates

Ameliorating end-product inhibition to improve cadaverine production in engineered Escherichia coli and its application in the synthesis of bio-based diisocyanates

Cadaverine is an important C5 platform chemical with a wide range of industrial applications. However, the cadaverine inhibition on the fermenting strain limited its industrial efficiency of the strain. In this study, we report an engineered Escherichia coli strain with high cadaverine productivity...

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Bibliographic Details
Main Authors: Xin Wang, Xing Guo, Jing Wang, Hui Li, Feng He, Sheng Xu, Kequan Chen, Pingkai Ouyang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-12-01
Series:Synthetic and Systems Biotechnology
Subjects:
Cadaverine
End-product inhibition
Escherichia coli
Transcriptome analysis
Metabolic engineering
Bio-based diisocyanate
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X21000478

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http://www.sciencedirect.com/science/article/pii/S2405805X21000478

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