Irisin alleviates obesity-related spermatogenesis dysfunction via the regulation of the AMPKα signalling pathway

Abstract Background Infertility is a common complication in obese men. Oxidative stress and testicular apoptosis play critical roles in obesity-induced spermatogenesis dysfunction. It has been reported that irisin, an exercise-induced myokine, may attenuate oxidative damage and testicular apoptosis...

Full description

Bibliographic Details
Main Authors: Yang Mu, Huang-Guan Dai, Ling-Bo Luo, Jing Yang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Reproductive Biology and Endocrinology
Subjects:
HFD
Online Access:https://doi.org/10.1186/s12958-021-00821-1