Rutin Modulates MAPK Pathway Differently from Quercetin in Angiotensin II-Induced H9c2 Cardiomyocyte Hypertrophy

Rutin Modulates MAPK Pathway Differently from Quercetin in Angiotensin II-Induced H9c2 Cardiomyocyte Hypertrophy

Rutin is a flavonoid with antioxidant property. It has been shown to exert cardioprotection against cardiomyocyte hypertrophy. However, studies regarding its antihypertrophic property are still lacking, whether it demonstrates similar antihypertrophic effect to its metabolite, quercetin. Hence, this...

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Bibliographic Details
Main Authors: Hawa Nordin Siti, Juriyati Jalil, Ahmad Yusof Asmadi, Yusof Kamisah
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
flavonoids
cardiomyocyte hypertrophy
ERK
JNK
p38 kinase
inducible nitric oxide synthase
Online Access:https://www.mdpi.com/1422-0067/22/10/5063

Internet

https://www.mdpi.com/1422-0067/22/10/5063

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