Transcriptional Differences between Normal and Glioma-Derived Glial Progenitor Cells Identify a Core Set of Dysregulated Genes

Glial progenitor cells (GPCs) are a potential source of malignant gliomas. We used A2B5-based sorting to extract tumorigenic GPCs from human gliomas spanning World Health Organization grades II–IV. Messenger RNA profiling identified a cohort of genes that distinguished A2B5+ glioma tumor progenitor...

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Bibliographic Details
Main Authors: Romane M. Auvergne, Fraser J. Sim, Su Wang, Devin Chandler-Militello, Jaclyn Burch, Yazan Al Fanek, Danielle Davis, Abdellatif Benraiss, Kevin Walter, Pragathi Achanta, Mahlon Johnson, Alfredo Quinones-Hinojosa, Sridaran Natesan, Heide L. Ford, Steven A. Goldman
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713002179