CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis.

CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis.

CCN2/Connective Tissue Growth Factor (CTGF) is a matricellular protein that regulates cell adhesion, migration, and survival. CCN2 is best known for its ability to promote fibrosis by mediating the ability of transforming growth factor β (TGFβ) to induce excess extracellular matrix production. In ad...

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Bibliographic Details
Main Authors: Faith Hall-Glenn, R Andrea De Young, Bau-Lin Huang, Ben van Handel, Jennifer J Hofmann, Tom T Chen, Aaron Choi, Jessica R Ong, Paul D Benya, Hanna Mikkola, M Luisa Iruela-Arispe, Karen M Lyons
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3282727?pdf=render

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http://europepmc.org/articles/PMC3282727?pdf=render

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