Natural Products Extracted from Fungal Species as New Potential Anti-Cancer Drugs: A Structure-Based Drug Repurposing Approach Targeting HDAC7

Natural Products Extracted from Fungal Species as New Potential Anti-Cancer Drugs: A Structure-Based Drug Repurposing Approach Targeting HDAC7

Mushrooms can be considered a valuable source of natural bioactive compounds with potential polypharmacological effects due to their proven antimicrobial, antiviral, antitumor, and antioxidant activities. In order to identify new potential anticancer compounds, an <i>in-house</i> chemica...

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Bibliographic Details
Main Authors: Annalisa Maruca, Roberta Rocca, Raffaella Catalano, Francesco Mesiti, Giosuè Costa, Delia Lanzillotta, Alessandro Salatino, Francesco Ortuso, Francesco Trapasso, Stefano Alcaro, Anna Artese
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
mushrooms
HDAC7
cancer
repositioning
structure-based virtual screening
molecular dynamics
Online Access:https://www.mdpi.com/1420-3049/25/23/5524

Internet

https://www.mdpi.com/1420-3049/25/23/5524

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