Key Genes and Pathways Associated With Inner Ear Malformation in SOX10 p.R109W Mutation Pigs

Key Genes and Pathways Associated With Inner Ear Malformation in SOX10 p.R109W Mutation Pigs

SRY-box 10 (SOX10) mutation may lead to inner ear deformities. However, its molecular mechanisms on inner ear development are not clear. In this work, the inner ear morphology was investigated at different embryonic stages of the SOX10 mutation miniature porcine model with sensorineural hearing loss...

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Bibliographic Details
Main Authors: Qing-Qing Hao, Liang Li, Wei Chen, Qing-Qing Jiang, Fei Ji, Wei Sun, Hong Wei, Wei-Wei Guo, Shi-Ming Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
SOX10
miniature pigs
mondini deformity
bioinformatics analysis
ceRNA network
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00181/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00181/full

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