Anti-PD-1 Therapy Response Predicted by the Combination of Exosomal PD-L1 and CD28

Anti-PD-1 Therapy Response Predicted by the Combination of Exosomal PD-L1 and CD28

Anti-PD-1 therapy has been approved for cancer treatment. However, the response rate is unsatisfactory. The expression of PD-L1 in tumor tissues is unreliable to predict the treatment response. Recent studies have suggested that exosomal PD-L1 not only exerts immunosuppressive effects but also plays...

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Bibliographic Details
Main Authors: Chaoxu Zhang, Yibo Fan, Xiaofang Che, Min Zhang, Zhi Li, Ce Li, Shuo Wang, Ti Wen, Kezuo Hou, Xinye Shao, Yunpeng Liu, Xiujuan Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Oncology
Subjects:
exosomal PD-L1
CD28
immune checkpoint inhibitor
response prediction
anti-PD-1 therapy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00760/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00760/full

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