CD100/Sema4D Increases Macrophage Infection by Leishmania (Leishmania) amazonensis in a CD72 Dependent Manner

Leishmaniasis is caused by trypanosomatid protozoa of the genus Leishmania, which infect preferentially macrophages. The disease affects 12 million people worldwide, who may present cutaneous, mucocutaneous or visceral forms. Several factors influence the form and severity of the disease, and the ma...

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Bibliographic Details
Main Authors: Mariana K. Galuppo, Eloiza de Rezende, Fabio L. Forti, Mauro Cortez, Mario C. Cruz, Andre A. Teixeira, Ricardo J. Giordano, Beatriz S. Stolf
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01177/full