Reconstruction and Validation of a Genome-Scale Metabolic Model of Streptococcus oralis (iCJ415), a Human Commensal and Opportunistic Pathogen

Reconstruction and Validation of a Genome-Scale Metabolic Model of Streptococcus oralis (iCJ415), a Human Commensal and Opportunistic Pathogen

The mitis group of streptococci (MGS) is a member of the healthy human microbiome in the oral cavity and upper respiratory tract. Troublingly, some MGS are able to escape this niche and cause infective endocarditis, a severe and devastating disease. Genome-scale models have been shown to be valuable...

Full description

Bibliographic Details
Main Authors: Christian S. Jensen, Charles J. Norsigian, Xin Fang, Xiaohui C. Nielsen, Jens Jørgen Christensen, Bernhard O. Palsson, Jonathan M. Monk
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Genetics
Subjects:
Streptococcus oralis
mitis group of streptococci
genome-scale reconstruction
constraint-based modeling
Biolog phenotypic profiling
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00116/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00116/full

Similar Items