Domain Requirements and Genetic Interactions of the Mud1 Subunit of the Saccharomyces cerevisiae U1 snRNP

Domain Requirements and Genetic Interactions of the Mud1 Subunit of the Saccharomyces cerevisiae U1 snRNP

Mud1 is an inessential 298-amino acid protein subunit of the Saccharomyces cerevisiae U1 snRNP. Mud1 consists of N-terminal and C-terminal RRM domains (RRM1 and RRM2) separated by a linker domain. Synthetic lethal interactions of mud1∆ with deletions of inessential spliceosome components Nam8, Mud2,...

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Bibliographic Details
Main Authors: Radhika Agarwal, Beate Schwer, Stewart Shuman
Format: Article
Language:English
Published: Oxford University Press 2019-01-01
Series:G3: Genes, Genomes, Genetics
Subjects:
pre-mRNA splicing
U1 snRNP
RRM domains
mutagenesis
synthetic lethality
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.118.200781

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http://g3journal.org/lookup/doi/10.1534/g3.118.200781

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