Cooperativity in RNA-Protein Interactions: Global Analysis of RNA Binding Specificity

Cooperativity in RNA-Protein Interactions: Global Analysis of RNA Binding Specificity

The control and function of RNA are governed by the specificity of RNA binding proteins. Here, we describe a method for global unbiased analysis of RNA-protein interactions that uses in vitro selection, high-throughput sequencing, and sequence-specificity landscapes. The method yields affinities fo...

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Bibliographic Details
Main Authors: Zachary T. Campbell, Devesh Bhimsaria, Cary T. Valley, Jose A. Rodriguez-Martinez, Elena Menichelli, James R. Williamson, Aseem Z. Ansari, Marvin Wickens
Format: Article
Language:English
Published: Elsevier 2012-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712001167

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http://www.sciencedirect.com/science/article/pii/S2211124712001167

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