Geraniol Pharmacokinetics, Bioavailability and Its Multiple Effects on the Liver Antioxidant and Xenobiotic-Metabolizing Enzymes

Geraniol Pharmacokinetics, Bioavailability and Its Multiple Effects on the Liver Antioxidant and Xenobiotic-Metabolizing Enzymes

Geraniol is a natural monoterpene showing anti-inflammatory, antioxidant, neuroprotective and anticancer effects. No pharmacokinetic and bioavailability data on geraniol are currently available. We therefore performed a systematic study to identify the permeation properties of geraniol across intest...

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Bibliographic Details
Main Authors: Barbara Pavan, Alessandro Dalpiaz, Luca Marani, Sarah Beggiato, Luca Ferraro, Donatella Canistro, Moreno Paolini, Fabio Vivarelli, Maria C. Valerii, Antonietta Comparone, Luigia De Fazio, Enzo Spisni
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Pharmacology
Subjects:
geraniol
gut
bioavailability
pharmacokinetics
xenobiotic-metabolizing enzymes
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00018/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00018/full

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