Renal Transplant Recipients Treated with Calcineurin-Inhibitors Lack Circulating Immature Transitional CD19+CD24hiCD38hi Regulatory B-Lymphocytes.

Renal Transplant Recipients Treated with Calcineurin-Inhibitors Lack Circulating Immature Transitional CD19+CD24hiCD38hi Regulatory B-Lymphocytes.

CD19+CD24hiCD38hi transitional immature B-lymphocytes have been demonstrated to play an important role in regulating the alloimmune response in transplant recipients. Here, we analyzed the effect of calcineurin inhibition on these peripherally circulating regulatory B-cells (Breg) in renal transplan...

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Bibliographic Details
Main Authors: Bastian Tebbe, Benjamin Wilde, Zeng Ye, Junyu Wang, Xinning Wang, Fu Jian, Sebastian Dolff, Manfred Schedlowski, Peter F Hoyer, Andreas Kribben, Oliver Witzke, André Hoerning
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4821620?pdf=render

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http://europepmc.org/articles/PMC4821620?pdf=render

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