Endothelial-Dependent and Independent Vascular Relaxation Effect of Tetrahydropalmatine on Rat Aorta

Endothelial-Dependent and Independent Vascular Relaxation Effect of Tetrahydropalmatine on Rat Aorta

Tetrahydropalmatine (THP) is an active natural alkaloid isolated from Corydalis yanhusuo W.T. Wang which has been widely used for treating pain and cardiovascular disease in traditional Chinese medicine. Previous studies suggested THP have various pharmacological effects in neural and cardio tissue...

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Bibliographic Details
Main Authors: Zhong-Yan Zhou, Wai-Rong Zhao, Wen-Ting Shi, Ying Xiao, Zi-Lin Ma, Jin-Gui Xue, Lun-Qing Zhang, Qing Ye, Xin-Lin Chen, Jing-Yi Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
Tetrahydropalmatine
vasorelaxation
calcium influx
endothelium function
potassium channel
calcium channel
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00336/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.00336/full

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