Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production
Increased triglyceride synthesis resulting from enhanced flux of fatty acids into liver is frequently associated with VLDL overproduction. This has led to the common belief that hepatic triglyceride synthesis can directly modulate VLDL production. We used adenoviral vectors containing either murine...
Main Authors: | John S. Millar, Scot J. Stone, Uwe J.F. Tietge, Bryan Tow, Jeffrey T. Billheimer, Jinny S. Wong, Robert L. Hamilton, Robert V. Farese, Jr., Daniel J. Rader |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2006-10-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520434170 |
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