The Emerging Role of Cyclin-Dependent Kinases (CDKs) in Pancreatic Ductal Adenocarcinoma

The Emerging Role of Cyclin-Dependent Kinases (CDKs) in Pancreatic Ductal Adenocarcinoma

The family of cyclin-dependent kinases (CDKs) has critical functions in cell cycle regulation and controlling of transcriptional elongation. Moreover, dysregulated CDKs have been linked to cancer initiation and progression. Pharmacological CDK inhibition has recently emerged as a novel and promising...

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Bibliographic Details
Main Authors: Balbina García-Reyes, Anna-Laura Kretz, Jan-Philipp Ruff, Silvia von Karstedt, Andreas Hillenbrand, Uwe Knippschild, Doris Henne-Bruns, Johannes Lemke
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
pancreatic cancer
pancreatic ductal adenocarcinoma
CDK
cyclin-dependent kinase
Online Access:http://www.mdpi.com/1422-0067/19/10/3219

Internet

http://www.mdpi.com/1422-0067/19/10/3219

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