Identification of the Key Role of NF-κB Signaling Pathway in the Treatment of Osteoarthritis With Bushen Zhuangjin Decoction, a Verification Based on Network Pharmacology Approach

Identification of the Key Role of NF-κB Signaling Pathway in the Treatment of Osteoarthritis With Bushen Zhuangjin Decoction, a Verification Based on Network Pharmacology Approach

This study aimed to identify whether the NF-κB signaling pathway plays a key role in the treatment of osteoarthritis (OA) with Bushen Zhuangjin Decoction (BZD) based on a typical network pharmacology approach (NPA). Four sequential experiments were performed: 1) conventional high-performance liquid...

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Bibliographic Details
Main Authors: Yunteng Xu, Hui Li, Xiaojuan He, Yanfeng Huang, Shengjie Wang, Lili Wang, Changlong Fu, Hongzhi Ye, Xihai Li, Tetsuya Asakawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
network pharmacology approach
complex herbal formulations
molecular targets
osteoarthritis
Bushen Zhuangjin decoction
NF-κB signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.637273/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.637273/full

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