Stable high frequencies of sulfadoxine–pyrimethamine resistance associated mutations and absence of K13 mutations in Plasmodium falciparum 3 and 4 years after the introduction of artesunate plus sulfadoxine–pyrimethamine in Ujjain, Madhya Pradesh, India

Stable high frequencies of sulfadoxine–pyrimethamine resistance associated mutations and absence of K13 mutations in Plasmodium falciparum 3 and 4 years after the introduction of artesunate plus sulfadoxine–pyrimethamine in Ujjain, Madhya Pradesh, India

Abstract Background Artesunate plus sulfadoxine–pyrimethamine (ASP) is first-line treatment for uncomplicated Plasmodium falciparum malaria in most of India, except for six North-eastern provinces where treatment failure rates were high. In Ujjain, central India, the frequency of mutations associate...

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Bibliographic Details
Main Authors: Ashish Pathak, Andreas Mårtensson, Sudhir Gawariker, Ashish Sharma, Vishal Diwan, Manju Purohit, Johan Ursing
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Artesunate sulfadoxine pyrimethamine
Chloroquine
Resistance
pfcrt
pfmdr1
Online Access:http://link.springer.com/article/10.1186/s12936-020-03274-w

Internet

http://link.springer.com/article/10.1186/s12936-020-03274-w

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