Trans-sialidase delivered as a naked DNA vaccine elicits an immunological response similar to a Trypanosoma cruzi infection

Trans-sialidase delivered as a naked DNA vaccine elicits an immunological response similar to a Trypanosoma cruzi infection

Trypanosoma cruzi, the protozoan parasite that causes Chagas' disease, does not synthesize sialic acid, but expresses a trans-sialidase (TS) that catalyzes the transfer of sialic acid from host glycoconjugates to the parasite surface. Here, we review studies that characterize the immune respons...

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Bibliographic Details
Main Authors: F. Costa, V.L. Pereira-Chioccola, M. Ribeirão, S. Schenkman, M.M. Rodrigues
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1999-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
DNA vaccination
Trans-sialidase
Chagas' disease
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000200013

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000200013

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