Circular RNA circFADS2 is overexpressed in sepsis and suppresses LPS-induced lung cell apoptosis by inhibiting the maturation of miR-15a-5p

Abstract Background Circular RNA circFADS2 plays protective roles in LPS-induced inflammation, which promotes sepsis, suggesting its involvement in sepsis. Methods Expression of circFADS2, mature miR-15a-5p, and miR-15a-5p precursor in plasma samples from sepsis patients and healthy controls was det...

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Bibliographic Details
Main Authors: Xiaoyang Hong, Shuanglei Li, Jie Wang, Zhe Zhao, Zhichun Feng
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Immunology
Subjects:
Online Access:https://doi.org/10.1186/s12865-021-00419-7