Hexosamine Biosynthetic Pathway and Glycosylation Regulate Cell Migration in Melanoma Cells

Hexosamine Biosynthetic Pathway and Glycosylation Regulate Cell Migration in Melanoma Cells

The Hexosamine Biosynthetic Pathway (HBP) is a branch of glycolysis responsible for the production of a key substrate for protein glycosylation, UDP-GlcNAc. Cancer cells present altered glucose metabolism and aberrant glycosylation, pointing to alterations on HBP. Recently it was demonstrated that H...

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Bibliographic Details
Main Authors: Rafaela Muniz de Queiroz, Isadora Araújo Oliveira, Bruno Piva, Felipe Bouchuid Catão, Bruno da Costa Rodrigues, Adriana da Costa Pascoal, Bruno Lourenço Diaz, Adriane Regina Todeschini, Michelle Botelho Caarls, Wagner Barbosa Dias
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Oncology
Subjects:
hexosamine biosynthetic pathway
O-GlcNAcylation
glycosylation
cell migration
melanoma
cancer
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00116/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00116/full

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