Effect of AGG Interruptions on FMR1 Maternal Transmissions

Effect of AGG Interruptions on FMR1 Maternal Transmissions

There are four classes of CGG repeat alleles in the FMR1 gene: normal alleles have up to 44 repeats; patients with Fragile X Syndrome have more than 200 repeats; those between 55 and 200 CGGs are considered FMR1 premutation alleles, because they are associated with maternal expansions of the number...

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Bibliographic Details
Main Authors: Olatz Villate, Nekane Ibarluzea, Hiart Maortua, Ana Belén de la Hoz, Laia Rodriguez-Revenga, Silvia Izquierdo-Álvarez, María Isabel Tejada
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
FMR1 gene
fragile X syndrome
CGG repeats
AGG interruptions
premutation
genetic counseling
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.00135/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2020.00135/full

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